Preheat the oven to 350 degrees.
Spread the nuts and pretzels on a clean, unlined sheet tray. Set aside.
In a small bowl, combine the melted butter, brown sugar, chipotle chili powder, maple syrup, orange juice, and salt. Stir until smooth.
Pour the spice mixture over the nuts and pretzels. Toss to combine until everything is evenly coated. Spread into an even layer on the sheet tray.
Bake for 12 minutes, stirring once mid-way through cooking to make sure the sauce doesn't burn on the edges. You will know the mixture is done cooking when the sauce thickens a bit and sticks to the nuts and pretzels. Everything will be a nice toasty brown, but nothing should be burned. Your kitchen will smell amazing!
Remove the tray from the oven and immediately give it a stir. Continue stirring every few minutes as the mixture cools to keep it from sticking. Once it has cooled completely, store in an air-tight container. It will stay fresh for several weeks.